Alexander Staruschenko
Alexander Staruschenko, Ph.D., Assistant Professor, Physiology

Alexander (Sasha) Staruschenko joined the Medical College of Wisconsin Department of Physiology as an Assistant Professor in November 2007.  Alexander is also a member of the Kidney Disease Center. 

Alexander (Sasha) Staruschenko joined the Medical College of Wisconsin Department of Physiology as an Assistant Professor in November 2007.  Alexander is also a member of the Kidney Disease Center. 

The Staruschenko Lab is interested in the normal and pathophysiological regulation of epithelial ion channels. A particular emphasis is placed on the epithelial Na+ channel (ENaC). The lab uses a number of contemporary methodologies, including electrophysiology, molecular biology, biochemistry, and fluorescence microscopy to investigate regulation of ENaC and aldosterone signaling. Currently it is working on projects including: 1) to determine the effects of small G proteins on ENaC activity and assign the cellular mechanism(s) of small G protein regulation of ENaC, 2) to identify the small G proteins responsible for trafficking of ENaC, 3) to identify cytoskeletal targets of small G proteins relevant to ENaC trafficking and their mechanism of action on the channel, 4) to determine which domains within ENaC subunits are necessary and modulatory for channel function, and 5) to identify which sequence tracts/domains within ENaC subunits are functional equivalent and which provide unique properties to the channel.

Education

M.S., Physiology, St. Petersburg State University, St. Petersburg, Russia, 1999 
Ph.D., Cell Biology, Institute of Cytology Russian Academy of Sciences, St. Petersburg, Russia, 2003
D.Sci., Cell Biology, Institute of Cytology Russian Academy of Sciences, St. Petersburg, Russia, 2010
Postdoctoral Fellow, Physiology, University of Texas Health Science Center at San Antonio, 2003-2007