Christopher Weber
Christopher Weber, MD, PhD, Assistant Professor, Pathology

Christopher Weber, MD, PhD, Assistant Professor, Pathology

Christopher Weber, MD, PhD, Assistant Professor, Pathology

Dr. Weber is a gastrointestinal pathologist at The University of Chicago. His major research focus is to understanding how epithelia form barriers between body compartments and how these barriers are altered in intestinal diseases such as Inflammatory Bowel Disease.  He received the Ueno Award for his work to define conductance across claudin-2 channels at a molecular level.  His studies are important because expression of claudin-2 is increased in inflammatory bowel disease and is believed to contribute to diarrhea.  His work demonstrates that claudin-2 channels are highly dynamic and open and close rapidly to define paracellular permeability to small cations such as sodium.  This finding suggests a potential novel means to treat barrier dysfunction might be to modulate the frequency and duration of claudin-2 openings and closings.

Education

B.S., Bioengineering, University of Illinois, 1995
M.D./Ph.D., Medicine/Physiology, Stritch School of Medicine/Loyola University of Chicago, 2004
Resident, Anatomic Pathology, The University of Chicago, 2004-2007
Postdoctoral Fellow, The University of Chicago, 2007-2010